Santa Maria Novella Vacations from $1,102

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Maria Novella Vacation

Renowned for its culture and cafes, Santa Maria Novella draws visitors from here, there and everywhere. Let our Santa Maria Novella vacation packages give you a peek into this neighborhood and all the awesome things it has to offer. Kick off your trip to Santa Maria Novella by heading to nearby attractions such as Basilica of Santa Maria Novella, Piazza di Santa Maria Novella and Fortezza da Basso. Stop dreaming and start doing. When it's time to book your dream vacation to Santa Maria Novella, Expedia will help you get there.

The Latest Santa Maria Novella Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Maxim Axial

Maxim Axial

3 out of 5
Historic Centre of Florence
Price was $1,571, price is now $1,102 per person
$1,102
per person
Apr 15 - Apr 21
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.6/10 Excellent! (1,002 reviews)
Great location and wonderful room! Will book again!

Reviewed on Mar 6, 2026

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $2,160, price is now $1,141 per person
$1,141
per person
Apr 15 - Apr 21
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
It was near the train and next to awesome places. The view if you get a balcony is so cute and peaceful

Reviewed on Feb 28, 2026

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $2,236, price is now $1,217 per person
$1,217
per person
May 13 - May 18
found 13 hours ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
7.6/10 Good! (1,000 reviews)
Smaller room then expected and shower did flood the floor so not the best of showers. Bed very comfortable Nice friendly & helpful staff and perfect location to explore the city.

Reviewed on Feb 22, 2026

Eurostars Florence Boutique

Eurostars Florence Boutique

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $1,959, price is now $1,189 per person
$1,189
per person
May 13 - May 18
found 13 hours ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
8.6/10 Excellent! (483 reviews)
The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants.

Reviewed on Dec 13, 2025

Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $3,205, price is now $2,213 per person
$2,213
per person
May 21 - May 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.8/10 Excellent! (965 reviews)
Close to everything!! That is a plus, however, room was warm and no screams on the windows. Several mosquito bites

Reviewed on Mar 6, 2026

Where to stay in Santa Maria Novella

Find the best Santa Maria Novella areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria Novella
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santa Maria Novella Hotel Deals

c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Via Luigi Alamanni 3 Florence FI
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $138 total per night from Mar 9 to Mar 10
$138 total
Mar 9 - Mar 10
Total with taxes and fees
8.2/10 Very Good! (1,001 reviews)
It was amazing and clean and really really perfect

Reviewed on Feb 17, 2026

c-hotels Ambasciatori
Hotel Machiavelli Palace

Hotel Machiavelli Palace

3 out of 5
Via Nazionale 10 Florence FI
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $129 total per night from Mar 15 to Mar 16
$129 total
Mar 15 - Mar 16
Total with taxes and fees
8.4/10 Very Good! (168 reviews)
The location was perfect, close to train station and local restaurants. The rooms were large and lovely, very clean. Staff was friendly and helpful.

Reviewed on Mar 3, 2026

Hotel Machiavelli Palace
Aurum Firenze

Aurum Firenze

4 out of 5
Via Nazionale 8/a Florence FI
$218 nightly
The price is $256 total per night from Mar 9 to Mar 10
$256 total
Mar 9 - Mar 10
Total with taxes and fees
7.6/10 Good! (1,007 reviews)
It was near the train and next to awesome places. The view if you get a balcony is so cute and peaceful

Reviewed on Feb 28, 2026

Aurum Firenze
See all 782 properties in Santa Maria Novella
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Maria Novella

Santa Maria Novella showing a church or cathedral, street scenes and heritage architecture

Basilica of Santa Maria Novella

4.5/5(1,006 reviews)

Experience the splendor of a centuries-old church that inspired leading artists from the Middle Ages and Renaissance.

Basilica of Santa Maria Novella
the ancient military fort Fortezza da Basso, now it is home to conferences, concerts and exhibitions

Fortezza da Basso

4.5/5(78 reviews)

Learn about the events happening at Fortezza da Basso during your trip to Florence. Discover the area's fascinating museums and churches.

Fortezza da Basso
The New Florence Opera House

The New Florence Opera House

Enjoy a performance at The New Florence Opera House, a storied theater in Porta al Prato. Discover the acclaimed art scene and churches in this family-friendly area.

The New Florence Opera House

Things to do

Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

$26
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Micheal Angelo's David

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

$37
per adult
86% of travellers recommend
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Uffizi Gallery Small-Group Guided Tour with Skip-the-Line

Uffizi Gallery: Small Group Guided Tour or Reserved Entry Ticket

$50
per adult
86% of travellers recommend
Uffizi Gallery: Small Group Guided Tour or Reserved Entry Ticket
See all activities in Florence

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.