Santa Maria Novella Vacations from $1,148
Book a Hotel + Flight or Car together to unlock savings
Your Santa Maria Novella Vacation
Renowned for its culture and cafes, Santa Maria Novella draws visitors from here, there and everywhere. Let our Santa Maria Novella vacation packages give you a peek into this neighborhood and all the awesome things it has to offer. Kick off your trip to Santa Maria Novella by heading to nearby attractions such as Basilica of Santa Maria Novella, Piazza di Santa Maria Novella and Fortezza da Basso. Stop dreaming and start doing. When it's time to book your dream vacation to Santa Maria Novella, Expedia will help you get there.
The Latest Santa Maria Novella Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Palazzo Lorenzo Hotel Boutique & Spa
San Lorenzo
$1,148
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
9.4/10 Exceptional! (622 reviews)
It is an excellent place to stay - closer to the train station-10 minutes.
Kept very clean and nice size of room
Breakfast was great
Very helpful staff.
Reviewed on Oct 16, 2026
Monastero di Cortona Hotel & Spa
Cortona Old Town
$1,506
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
10/10 Exceptional! (337 reviews)
Awesome spot to stay, staff treats you like royalty. Nice little spot to stay for a few days after one of the bigger cities in Italy!
Reviewed on Oct 19, 2026
Where to stay in Santa Maria Novella
Find the best Santa Maria Novella areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria Novella
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Santa Croce
One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella Hotel Deals
The Social Hub Florence Belfiore
Viale Belfiore, 55 Florence FI
Fully refundableReserve now, pay when you stay
$64 nightly
$87 total
Nov 15 - Nov 16
Total with taxes and fees
Hotel Albani Firenze
Via Fiume 12 Florence FI
Fully refundableReserve now, pay when you stay
$106 nightly
$132 total
Nov 18 - Nov 19
Total with taxes and fees
9.2/10 Wonderful! (1,012 reviews)
"Unique rooms. Great walking distance to food and shops while also being close to the train station for convince. Everything was clean and lots of warm towels and nice robe! Would definitely stay here again traveling through Florence."
Reviewed on Oct 19, 2026
Hotel Santa Maria Novella
Piazza Santa Maria Novella 1 Florence FI
Fully refundableReserve now, pay when you stay
$169 nightly
$201 total
Nov 19 - Nov 20
Total with taxes and fees
9.6/10 Exceptional! (1,002 reviews)
"We loved it. Highly recommend"
Reviewed on Oct 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Maria Novella attractions
Fortezza da Basso
8.4/10 (260 reviews)
Learn about the events happening at Fortezza da Basso during your trip to Florence. Discover the area's acclaimed art scene and stunning cathedral.
Basilica of Santa Maria Novella
9.4/10 (5,881 reviews)
Experience the splendor of a centuries-old church that inspired leading artists from the Middle Ages and Renaissance.
The New Florence Opera House
Enjoy a performance at The New Florence Opera House, a storied theater in Florence. Discover the acclaimed art scene and churches in this family-friendly area.
Palazzo dei Congressi
8.6/10 (27 reviews)
After visiting Palazzo dei Congressi, make a plan to see the other sights and activities in Florence. Discover the area's acclaimed art scene and stunning cathedral.
Leopolda Station Exhibition Center
Learn about the events happening at Leopolda Station Exhibition Center during your trip to Florence. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Piazza Ognissanti
9.0/10 (2 reviews)
You can learn about the history of Florence with a trip to Piazza Ognissanti. Visit the notable monuments and stunning cathedral in this vibrant area.
Stazione Leopolda
Learn about the events happening at Stazione Leopolda during your trip to Florence. Check out the churches and charming cafes in this walkable area.
National Alinari Museum of Photography
You can browse the exhibits at National Alinari Museum of Photography, a museum with a storied past, during your travels to Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.
Things to do
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
$21
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
$21
per adult
94% of travellers recommend
Accademia timed-entry Ticket with App Guide
$45
per adult
90% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.