Santa Maria Novella Vacations from $1,004
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Your Santa Maria Novella Vacation
Renowned for its culture and cafes, Santa Maria Novella draws visitors from here, there and everywhere. Let our Santa Maria Novella vacation packages give you a peek into this neighborhood and all the awesome things it has to offer. Kick off your trip to Santa Maria Novella by heading to nearby attractions such as Basilica of Santa Maria Novella, Piazza di Santa Maria Novella and Fortezza da Basso. Stop dreaming and start doing. When it's time to book your dream vacation to Santa Maria Novella, Expedia will help you get there.
The Latest Santa Maria Novella Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Donati Luxury Tower Suites
Historic Centre of Florence
$1,980
per person
Dec 12 - Dec 19
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.8/10 Exceptional! (73 reviews)
We loved this property. The room and view are beautiful. There are excellent restaurants and shopping around the corner.
Reviewed on Sep 21, 2026
Where to stay in Santa Maria Novella
Find the best Santa Maria Novella areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria Novella
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Santa Croce
One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella Hotel Deals
The Social Hub Florence Belfiore
Viale Belfiore, 55 Florence FI
Fully refundableReserve now, pay when you stay
$129 nightly
$158 total
Oct 25 - Oct 26
Total with taxes and fees
9.4/10 Exceptional! (755 reviews)
"It's easy to reach on the tram, has good food, and is close to the center.I had a really good stay. The accommodations were comfortable, and everything went smoothly. I'd definitely recommend this place!"
Reviewed on Sep 27, 2026
Hotel Albani Firenze
Via Fiume 12 Florence FI
$188 nightly
$223 total
Oct 22 - Oct 23
Total with taxes and fees
9.2/10 Wonderful! (1,010 reviews)
"The croissants and cappuccinos at breakfast were delicious. It was in a good location, close to the train station. The room and staff were decent."
Reviewed on Sep 27, 2026
c-hotels Ambasciatori
Via Luigi Alamanni 3 Florence FI
$230 nightly
$269 total
Oct 27 - Oct 28
Total with taxes and fees
8.2/10 Very Good! (1,005 reviews)
"This hotel is one of my favourite places to stay. The Hotel is ideally situated two minutes from Santa Maria Novella train station. The hotel is clean and the staff are good. My only downside - when I arrived the man on reception told me I had not paid for breakfast. As a result I only went down ..."
Reviewed on Sep 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Maria Novella attractions
Basilica of Santa Maria Novella
9.4/10 (5,881 reviews)
Experience the splendor of a centuries-old church that inspired leading artists from the Middle Ages and Renaissance.
Fortezza da Basso
8.4/10 (260 reviews)
Learn about the events happening at Fortezza da Basso during your trip to Florence. Discover the area's acclaimed art scene and stunning cathedral.
The New Florence Opera House
Enjoy a performance at The New Florence Opera House, a storied theater in Porta al Prato. Discover the acclaimed art scene and churches in this family-friendly area.
Chiesa di Ognissanti
8.0/10 (2 reviews)
Get close to works by acclaimed Renaissance artists, such as Botticelli and Giotto, in one of the earliest baroque-style churches built in Florence.
Palazzo dei Congressi
8.6/10 (27 reviews)
After visiting Palazzo dei Congressi, make a plan to see the other sights and activities in Florence. Discover the area's acclaimed art scene and stunning cathedral.
Leopolda Station Exhibition Center
Learn about the events happening at Leopolda Station Exhibition Center during your trip to Porta al Prato. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Piazza Ognissanti
9.0/10 (2 reviews)
You can learn about the history of Florence with a trip to Piazza Ognissanti. Visit the notable monuments and stunning cathedral in this vibrant area.
Palazzo degli Affari
8.4/10 (5 reviews)
After visiting Palazzo degli Affari, make a plan to see the other sights and activities in Florence. Visit the area's stunning cathedral or amble around its riverfront.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$33
per adult
76% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
$21
per adult
94% of travellers recommend
Accademia timed-entry Ticket with App Guide
$45
per adult
90% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.