Name: c-hotels Ambasciatori
Price range: $92 total

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Your Santa Maria Novella Vacation

Renowned for its culture and cafes, Santa Maria Novella draws visitors from here, there and everywhere. Let our Santa Maria Novella vacation packages give you a peek into this neighborhood and all the awesome things it has to offer. Kick off your trip to Santa Maria Novella by heading to nearby attractions such as Basilica of Santa Maria Novella, Piazza di Santa Maria Novella and Fortezza da Basso. Stop dreaming and start doing. When it's time to book your dream vacation to Santa Maria Novella, Expedia will help you get there.

The Latest Santa Maria Novella Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Aurum Uffizi

Historic Centre of Florence

$786

per person

Jan 14 - Jan 17

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Florence (FLR)

7.6/10 Good! (1,003 reviews)

Relais Uffizi, Tailor made Hotel

Historic Centre of Florence

$1,222

per person

Jan 14 - Jan 20

found 1 day ago

Roundtrip non-stop flight included

New York (NYC) to Florence (FLR)

9.2/10 Wonderful! (177 reviews)

We loved the location and proximity to major attractions and great restaurants. Breakfast in the morning was delicious and in a lovely space. Our room was spacious, unfortunately it smelled like mildew. Our travel companions had the room next door which did not have the same issue. We also experienced a lot of noise in the middle of the night on two of the four nights we stayed. Overall, I would recommend this hotel, just a different hotel room in the future.

Reviewed on Nov 3, 2026

Hotel Duomo Firenze

Historic Centre of Florence

$1,387

per person

Jan 24 - Jan 28

found 1 day ago

Roundtrip non-stop flight included

Seattle (SEA) to Florence (FLR)

9.2/10 Wonderful! (1,003 reviews)

Amazing location. So cool to be literally across from the Duomo. Easy walk to so many places to shop and eat. Free sparkling and still water was great. Snacks and free gelato! Staff was the most friendly and helpful. Highly recommend this place!

Reviewed on Nov 3, 2026

Hotel Regency

Historic Centre of Florence

$3,144

per person

Dec 27 - Jan 2

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Florence (FLR)

9.4/10 Exceptional! (469 reviews)

The Place Firenze

Historic Centre of Florence

$8,371

per person

Dec 27 - Jan 3

found 3 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Florence (FLR)

9.8/10 Exceptional! (203 reviews)

Where to stay in Santa Maria Novella

Find the best Santa Maria Novella areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria Novella

A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Santa Maria Novella Hotel Deals

The Social Hub Florence Belfiore

Viale Belfiore, 55 Florence FI

Fully refundableReserve now, pay when you stay

$58 nightly

$79 total

Nov 15 - Nov 16

Total with taxes and fees

9.4/10 Exceptional! (812 reviews)

"Good gym"

Reviewed on Nov 9, 2026

Hotel Albani Firenze

Via Fiume 12 Florence FI

Fully refundableReserve now, pay when you stay

$105 nightly

$131 total

Dec 11 - Dec 12

Total with taxes and fees

9.2/10 Wonderful! (1,002 reviews)

"Great location...near station but a queit street. Elegant ambiance. Great breakfast. Provides umbrellas!"

Reviewed on Nov 11, 2026

c-hotels Ambasciatori

Via Luigi Alamanni 3 Florence FI

Fully refundableReserve now, pay when you stay

$70 nightly

$92 total

Nov 15 - Nov 16

Total with taxes and fees

See all 797 properties in Santa Maria Novella

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.